Poniżej przedstawiamy listę dotychczasowych publikacji, w których wykorzystano frakcjonator OffGel 3100 firmy Agilent:
Basic Research
- Johannes Graumann, Nina C. Hubner, Jeong Beom Kim, Kinarm Ko, Markus Moser, Chanchal Kumar, Jürgen Cox, Hans Schöler, and Matthias Mann, Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Proteome Quantitation of Mouse Embryonic Stem Cells to a Depth of 5,111 Proteins, Mol Cell Proteomics, 7, Apr 2008
- Michael C. M. Kwok, Juha M. Holopainen, Laurie L. Molday, Leonard J. Foster, and Robert S. Molday, Proteomics of Photoreceptor Outer Segments Identifies a Subset of SNARE and Rab Proteins Implicated in Membrane Vesicle Trafficking and Fusion, Mol Cell Proteomics, 7, Jun 2008
Biomarker
- Jennifer A. Burgess, Pierre Lescuyer, Alexandre Hainard, Pierre R. Burkhard, Natacha Turk, Philippe Michel, Joel S. Rossier, Frederic Reymond, Denis F. Hochstrasser, Jean-Charles Sanchez, Identification of brain cell death associated proteins in human post-mortem cerebrospinal fluid, J Proteome Res, 5(7), Jun 2006
- Hiroshi Sezaki and Kiyonobu Fukunaga, Proteomics of plasma protein by MUDPIT, SEIBUTSU BUTSURI KAGAKU, 51, Jan 2007
Diagnostics
- J Maxwell Silverman, Simon K Chan, Dale P Robinson, Dennis M Dwyer , Devki Nandan, Leonard J Foster and Neil E Rein, Proteomic analysis of the secretome of Leishmania donovani, Genome Biology, 9, Feb 2008
- Sricharan Bandhakavi, Matthew D. Stone, Getiria Onsongo, Susan K. Van Riper and Timothy J. Griffin, A Dynamic Range Compression and Three-Dimensional Peptide Fractionation Analysis Platform Expands Proteome Coverage and the Diagnostic Potential of Whole Saliva, J Proteome Res, ASAP, Oct 2009
- Jerome Chenau, Sylvie Michelland, Florence de Fraipont, Vronique Josserand, Jean-Luc Coll, Marie-Christine Favrot and Michel Seve, The Cell Line Secretome, a Suitable Tool for Investigating Proteins Released in Vivo by Tumors: Application to the Study of p53-Modulated Proteins Secreted in Lung Cancer Cells, J Proteome Res, 8 (10), Jul 2009
Disease Discovery
- Jeffrey F. Kuhn, Patric Hoerth, Silvia T. Hoehn, Tobias Preckel, Kenneth B. Tomer, Proteomics study of anthrax lethal toxin-treated murine macrophages, Electrophoresis, 27(8), Apr 2006
- Jason Mulvenna, Brett Hamilton, Shivashankar H. Nagaraj, Danielle Smyth, Alex Loukas, and Jeffrey J. Gorman, Proteomics Analysis of the Excretory/Secretory Component of the Blood-feeding Stage of the Hookworm, Ancylostoma caninum, Mol Cell Proteomics, 8, Jan 2009
- Francesca Forner, Chanchal Kumar, Christian A. Luber, Tobias Fromme, Martin Klingenspor, Matthias Mann, Proteome Differences between Brown and White Fat Mitochondria Reveal Specialized Metabolic Functions, Cell Metabolism, 10(4), Oct 2009
Doping Control
- Maxie Kohler, Andreas Thomas, Klaus Pschel, Wilhelm Schnzer and Mario Thevis, Identification of Human Pituitary Growth Hormone Variants by Mass Spectrometry, J Proteome Res, 8(2), Jan 2009
Drug Development
- Jason Mulvenna, Luke Moertel, Malcolm K. Jones, Sujeevi Nawaratna, Erica M. Lovas, Geoffrey N. Gobert, Michelle Colgrave, Alun Jones, Alex Loukas, Donald P. McManus, Exposed proteins of the Schistosoma japonicum tegument, International Journal for Parasitology, Oct 2009
Methodology
- Cuiping Pan, Chanchal Kumar, Sebastian Bohl, Ursula Klingmueller, and Matthias Mann, Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions, Mol Cell Proteomics, 8, Mar 2009
- Philippe E. Michel, Frédéric Reymond, Isabelle L. Arnaud, Jacques Josserand, Hubert H. Girault, Joel S. Rossier, Protein fractionation in a multicompartment device using Off-Gel isoelectric focusing, Electrophoresis, 24, Jan 2003
- Heller M., Michel P. E., Morier P., Crettaz D., Wenz C., Tissot J. D., Reymond F. and Rossier J. S., Two-stage Off-Gel isoelectric focusing: protein followed by peptide fractionation and application to proteome analysis of human plasma, Electrophoresis, 26(6), Feb 2005
- Heller M., Ye M., Michel P. E., Morier P., Stalder D., Junger M. A., Aebersold R., Reymond F. and Rossier J. S., Added value for tandem mass spectrometry shotgun proteomics data validation through isoelectric focusing of peptides, J Proteome Res, 4(6), Oct 2005
- Michel P. E., Crettaz D., Morier P., Heller M., Gallot D., Tissot J. D., Reymond F. and Rossier J. S., Proteome analysis of human plasma and amniotic fluid by Off-Gel isoelectric focusing followed by nano-LC-MS/MS, Electrophoresis, 27(5-6), Mar 2006
- Patric Hoerth, Christine A. Miller, Tobias Preckel, Christian Wenz, Efficient fractionation and improved protein identification by peptide OFFGEL electrophoresis, Mol Cell Proteomics, 5(10), Oct 2006
- Busnel J.-M., Lion N., Girault H.H., Capillary Electrophoresis as a Second Dimension to Isoelectric Focusing for Peptide Separation, Anal Chem, 79, Jun 2007
- Vitzthum F., Siest G., Bunk D.M., Preckel, T., Wenz C., Hoerth, P., Schulz-Knappe P., Tammen H., Adamkiewicz J., Merlini G., Anderson N.L., Metrological sharp shooting for plasma proteins and peptides: The need for reference materials for accurate measurements in clinical proteomics and in vitro diagnostics to generate reliable results, Proteomics Clin Appl, 1, Aug 2007
- Paola Picotti, Ruedi Aebersold, and Bruno Domon, The Implications of Proteolytic Background for Shotgun Proteomics, Mol Cell Proteomics, 6, Sep 2007
- Hasmik Keshishian, Terri Addona, Michael Burgess, Eric Kuhn, and Steven A. Carr, Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution, Mol Cell Proteomics, 6, Dec 2007
- J. M. Chick, P. A. Haynes, M. P. Molloy, B. Bjellqvist, M. S. Baker and A. C. L. Len, Characterization of the Rat Liver Membrane Proteome Using Peptide Immobilized pH Gradient Isoelectric Focusing, J Proteome Res, 7(3), Jan 2008
- Chenau J., Michelland S., Sidibe J., Seve M, Peptides OFFGEL electrophoresis: a suitable pre-analytical step for complex eukaryotic samples fractionation compatible with quantitative iTRAQ labeling, Proteome Sci, 26, Jan 2008
- John C. Tran and Alan A. Doucette, Rapid and Effective Focusing in a Carrier Ampholyte Solution Isoelectric Focusing System: A Proteome Prefractionation Tool, J Proteome Res, 7(4), Feb 2008
- Yassel Ramos, Elain Gutierrez, Yoan Machado, Aniel Snchez, Lila Castellanos-Serra, Luis J. Gonzlez, Jorge Fernndez-de-Cossio, Yasset Prez-Riverol, Lzaro Betancourt, Jeovanis Gil, Gabriel Padrn and Vladimir Besada, Proteomics Based on Peptide Fractionation by SDS-Free PAGE, J Proteome Res, 7(6), Apr 2008
- Vinzenz Lange, Johan A. Malmström, John Didion, Nichole L. King, Björn P. Johansson, Juliane Schäfer, Jonathan Rameseder, Chee-Hong Wong, Eric W. Deutsch, Mi-Youn Brusniak, Peter Bühlmann, Lars Björck, Bruno Domon, and Ruedi Aebersold, Targeted Quantitative Analysis of Streptococcus pyogenes Virulence Factors by Multiple Reaction Monitoring, Mol Cell Proteomics, 7, Aug 2008
- Tiziana Bonaldi, Tobias Straub, Jürgen Cox, Chanchal Kumar, Peter B. Becker, Matthias Mann, Combined Use of RNAi and Quantitative Proteomics to Study Gene Function in Drosophila, Mol Cell, 31(5), Sep 2008
- Susann Schenk , Gary J Schoenhals , Gustavo de Souza and Matthias Mann, A high confidence, manually validated human blood plasma protein reference set, BMC Medical Genomics, 1, Sep 2008
- Waller L.N., Shores K., Knapp D.R., Shotgun Proteomic Analysis of Cerebrospinal Fluid Using Off-Gel Electrophoresis as the First-Dimension Separation, J Proteome Res, 7(10), Sep 2008
- Lyris M. F. de Godoy, Jesper V. Olsen, Jürgen Cox, Michael L. Nielsen, Nina C. Hubner, Florian Fröhlich, Tobias C. Walther, Matthias Mann, Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast, Nature, 455, Sep 2008
- Sara Zanivan, Florian Gnad, Sara A. Wickstrm, Tami Geiger, Boris Macek, Jrgen Cox, Reinhard Fssler and Matthias Mann, Solid Tumor Proteome and Phosphoproteome Analysis by High Resolution Mass Spectrometry, J Proteome Res, 7(12), Oct 2008
- Ernoult E., Gamelin E., Guette C., Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation, Proteome Sci, 6(7), Oct 2008
- Daniel B. Martin, Ted Holzman, Damon May, Amelia Peterson, Ashley Eastham, Jimmy Eng, and Martin McIntosh, MRMer, an Interactive Open Source and Cross-platform System for Data Extraction and Visualization of Multiple Reaction Monitoring Experiments, Mol Cell Proteomics, 7(11), Nov 2008
- Hubner N.C., Ren S., Mann M., Peptide separation with immobilized pI strips is an attractive alternative to in-gel protein digestion for proteome analysis, Proteomics, 8(23-24), Dec 2008
- Jürgen Cox, Matthias Mann, MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification, Nature Biotech, 26, Dec 2008
- Laura Hohmann, Carly Sherwood, Ashley Eastham, Amelia Peterson, Jimmy K. Eng, James S. Eddes, David Shteynberg and Daniel B. Martin, Proteomic Analyses Using Grifola frondosa Metalloendoprotease Lys-N, J Proteome Res, 8(3), Feb 2009
- Jacek R Wisniewski , Alexandre Zougman , Nagarjuna Nagaraj & Matthias Mann, Universal sample preparation method for proteome analysis, Nature Methods, 6, May 2009
- Carly A. Sherwood, Ashley Eastham, Lik Wee Lee, Jenni Risler, Olga Vitek and Daniel B. Martin, Correlation between y-Type Ions Observed in Ion Trap and Triple Quadrupole Mass Spectrometers, J Proteome Res, 8(9), Jul 2009
- Hu Zhou, Weimin Hou, Jean-Philippe Lambert, Ruijun Tian, Daniel Figeys, Analysis of low-abundance proteins using the proteomic reactor with pH fractionation, Talanta, Jul 2009
- Picotti P., Bodenmiller B., Mueller L.N., Aebersold R., Full Dynamic Range Proteome Analysis of S. cerevisiae by Targeted Proteomics, Cell, 138(4), Aug 2009
- Sarah Elschenbroich, Vladimir Ignatchenko, Parveen Sharma, Gerold Schmitt-Ulms, Anthony O. Gramolini and Thomas Kislinger, Peptide Separations by On-Line MudPIT Compared to Isoelectric Focusing in an Off-Gel Format: Application to a Membrane-Enriched Fraction from C2C12 Mouse Skeletal Muscle Cells, J Proteome Res, 8(10), Oct 2009
- Emilie Ernoult, Anthony Bourreau, Erick Gamelin, and Catherine Guette, A Proteomic Approach for Plasma Biomarker Discovery with iTRAQ Labelling and OFFGEL Fractionation, J Biomed Biotechnol, Nov 2009
- Lam H.T., Josserand J., Lion, N., Girault, H.H., Modeling the Isoelectric Focusing of Peptides in an OFFGEL Multicompartment Cell, J Proteome Res, 6(5), Mar 2007
- Fraterman S., Zeiger U., Khurana T.S., Rubinstein N.A., Wilm M., Combination of peptide OFFGEL fractionation and label-free quantitation facilitated proteomics profiling of extraocular muscle, Proteomics, 7, Aug 2007
- Graumann J., Hubner N.C., Kim J.B., Ko K., Moser M., Kumar C., Cox J., Schöler H., Mann M., SILAC-labeling and proteome quantitation of mouse embryonic stem cells to a depth of 5111 proteins, Mol Cell Proteomics, 7(4), Apr 2008
- Lottspeich F, Separation sciences in the era of proteomics, Electrophoresis, 29, Jun 2008
- Cuiping Pan, Jesper V. Olsen, Henrik Daub, and Matthias Mann, Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics, Mol Cell Proteomics, in press, Aug 2009
- Boumediene Soufi, Christian D. Kelstrup, Gabriele Stoehr, Florian Fröhlich, Tobias C. Walther and Jesper V. Olsen, Global analysis of the yeast osmotic stress response by quantitative proteomics, Mol BioSyst, 5, Sep 2009
- Martin Beck, Johan A Malmström, Vinzenz Lange, Alexander Schmidt, Eric W Deutsch, Ruedi Aebersold, Visual proteomics of the human pathogen Leptospira interrogans, Nature Methods, 6, Oct 2009
- Melinda E. Lull, Willard M. Freeman, Heather D. VanGuilder, Kent E. Vrana, The use of neuroproteomics in drug abuse research, Drug and Alcohol Dependence, Nov 2009
